5-Bromouracil (BU) resembles thymine suciently that BU base-pairs readily with adenine in a DNA helix, and it

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5-Bromouracil (BU) resembles thymine sufficiently that BU base-pairs readily with adenine in a DNA helix, and it can readily substitute for thy-mine in DNA replication. However, its electron distribution allows it to resemble cytosine sufficiently that BU can pair with guanine. Show how a few rounds of replication in the presence of BU could convert an A-T base pair to G-C, and identify the products of each round of replication.
Distribution
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Biochemistry Concepts and Connections

ISBN: 978-0321839923

1st edition

Authors: Dean R. Appling, Spencer J. Anthony Cahill, Christopher K. Mathews

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