Alcohols undergo an oxidation reaction to yield carbonyl compounds on treatment with CrO 3 . For example,
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Alcohols undergo an oxidation reaction to yield carbonyl compounds on treatment with CrO3. For example, 2-tert-butylcyclohexanol gives 2-tert-butylcyclo- hexanone. If axial ?OH groups are generally more reactive than their equatorial isomers, which do you think would react faster, the cis isomer of 2?tert?butylcvclohexanol or the trans isomer? Explain.
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HO Cro3 C(CH3)3 C(CH3)3 2-tert-Butylcyclohexanol 2-tert-Butylcyclohexanone
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