Amino acids can he prepared by reaction of alkyl halides with diethyl acetamidomalonate, followed by heating the
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Amino acids can he prepared by reaction of alkyl halides with diethyl acetamidomalonate, followed by heating the initial alkylation product with aqueous lid. Show how you would prepare alanine, CH3CH(NH2) CO2H, one of the twenty amino acids found in proteins, and propose a mechanism for acid-catalyzed conversion of the initial alkylation product to the aminoacid.
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CH3CNHCHCOET Diethyl acetamidomalonate CO2Et
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CH3CNHCCOEt COEt HNCHCOH CH3 Alanine Na OEt formation of enolate i CH3...View the full answer
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