Aryl halides react too slowly to undergo substitution by the SN2 mechanism with the sodium salt of

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Aryl halides react too slowly to undergo substitution by the SN2 mechanism with the sodium salt of diethyl malonate, and so the phenyl substituent of phenobarbital cannot be introduced in the way that alkyl substituents can.
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Organic Chemistry

ISBN: 978-0072905014

4th edition

Authors: Francis A. Carey

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