Question: Biochemical connections We usually say that a perfect buffer has
Biochemical connections We usually say that a perfect buffer has its pH equal to its pKa. Give an example of a situation in which it would be advantageous to have a buffer with a pH 0.5 unit higher than its pKa.
Answer to relevant QuestionsWhich would you think would be a stronger interaction and why: an interaction between a sodium ion and the partial negative charge on the oxygen in ethanol (CH3CH2OH), or the interaction between two ethanol molecules? Based on the information in Table 3.2, is there any amino acid that could serve as a buffer at pH 8? If so, which one? If you knew everything about the properties of the 20 common (proteinous) amino acids, would you be able to predict the properties of a protein (or large peptide) made from them? What are Ramachandran angles? Describe the effect of 2,3-bisphosphoglycerate on the binding of oxygen by hemoglobin.
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