Describe the basic structure of class I and class II major histocompatibility complex (MHC) proteins. In what functional ways do they differ?
Answer to relevant QuestionsDifferentiate between Tc cells and NK cells. What is the activation signal for each cell type? What problems would arise if a person had a hereditary deficiency that resulted in an inability to present antigens to Tc cells? What would the problems be if the person had a deficiency in presenting antigen to Th1 cells? ...Which Ig chains are used to construct a complete antigen-binding site? Which domains? Which CDRs? What would be the result of activation of all T cells that contact antigen? How does the multiple signal mechanism prevent this from happening? Describe the standard procedure for obtaining and culturing a throat culture and a blood sample. What special precautions must be taken while obtaining the blood sample?
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