Describe the general mechanism used by superantigens to activate T cells. How does superantigen activation differ from T cell activation by conventional antigens?
Answer to relevant QuestionsIdentify the cells that express pattern recognition receptors (PRRs). How do PRRs associate with pathogen-associated molecular patterns (PAMPs) to promote innate immunity? Define the differences between immediate and delayed-type hypersensitivity in terms of immune effectors, target tissues, antigens, and clinical outcome. What molecules induce immune responses? What properties are necessary for a molecule to induce an immune response? Antibodies of the IgA class are probably more prevalent than those of the IgG class. Explain this and define the benefits this may have for the host. Explain positive and negative selection of T cells.
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