Do you agree with the following statement? Complement is a critical component of antibody-mediated defense. Explain your answer. What might happen to persons who lack complement component C3? C5? Factor B (alternative pathway)? Mannose-binding lectin (MBL)?
Answer to relevant QuestionsWhat are the major cytokines and their effects in an antibody-mediated response? In a Th1-mediated response? Calculate the total number of germ-line-encoded VH and VL domains that can be constructed from the available Ig genes. Compare this to the numbers of germ-line-encoded Vβ and Vα domains of the TCR. How is diversity ...What would be the result of activation of all T cells that contact antigen? How does the multiple signal mechanism prevent this from happening? Explain how selection for metabolic mutants can extend traditional methods of natural product selection for antibiotic discovery. Viruses and fungi present special problems for drug therapy. Explain the issues inherent in drug treatment of both groups and explain whether or not you agree with the preceding statement. Give specific examples and suggest ...
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