Explain how fructose-2,6-bisphosphate can play a role in more than one metabolic pathway.
Answer to relevant QuestionsHow can the synthesis and breakdown of fructose-2,6-bisphosphate be controlled independently? Explain how the pentose phosphate pathway can respond to a cell’s need for ATP, NADPH, and ribose-5- phosphate. How does substrate-level phosphorylation differ from phosphorylation linked to the electron transport chain? Using the information in Chapters 17–19, calculate the amount of ATP that can be produced from one molecule of lactose metabolized aerobically through glycolysis and the citric acid cycle. Comment on the fact that the reduction of pyruvate to lactate, catalyzed by lactate dehydrogenase, is strongly exergonic (recall this from Chapter 15), even though the standard free-energy change for the half ...
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