Explain positive and negative selection of T cells.
Answer to relevant QuestionsWhat molecular interactions are necessary for activation of uncommitted T cells? For activation of uncommitted B cells? Why is the immunoblot (Western blot) procedure used to confirm screening tests that are positive for human immunodeficiency virus (HIV)? Explain how selection for metabolic mutants can extend traditional methods of natural product selection for antibiotic discovery. Define the procedures you would use to isolate and identify a new pathogen. Keep in mind Koch’s postulates as you form your answer. Be sure to include growth-dependent assays, immunoassays, and molecular assays. Where ...Describe the major medical and public health measures developed in the twentieth century that were instrumental in controlling the spread of infectious diseases in developed countries.
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