# Question: In a standard dissolution test for tablets of a particular

In a standard dissolution test for tablets of a particular drug product, the manufacturer must obtain the dissolution rate for a batch of tablets prior to release of the batch. Suppose that the dissolution test consists of assays for 24 randomly selected individual 25 mg tablets. For each test, the tablet is suspended in an acid bath and then assayed after 30 minutes. The results of the 24 assays are given here.

a. Using a graphical display, determine whether the data appear to be a random sample from a normal distribution.

b. Estimate the mean dissolution rate for the batch of tablets, for both a point estimate and a 99% confidence interval.

c. Is there significant evidence that the batch of pills has a mean dissolution rate less than 20 mg (80% of the labeled amount in the tablets)? Use a = .01.

d. Calculate the probability of a Type II error if the true dissolution rate is 19.6 mg.

a. Using a graphical display, determine whether the data appear to be a random sample from a normal distribution.

b. Estimate the mean dissolution rate for the batch of tablets, for both a point estimate and a 99% confidence interval.

c. Is there significant evidence that the batch of pills has a mean dissolution rate less than 20 mg (80% of the labeled amount in the tablets)? Use a = .01.

d. Calculate the probability of a Type II error if the true dissolution rate is 19.6 mg.

**View Solution:**## Answer to relevant Questions

When an audit must be conducted that involves a tedious examination of a large inventory, the audit may be very costly and time consuming if each item in the inventory must be examined. In such situations, the auditor ...As part of an overall evaluation of training methods, an experiment was conducted to determine the average exercise capacity of healthy male army inductees. To do this, each male in a random sample of 35 healthy army ...Refer to Exercise 5.74. In exercise a. The cars in the study appear to have grossly different mileages before the devices were installed. Use the change data to test whether there has been a significant gain in mileage ...A firm has a generous but rather complicated policy concerning end-of-year bonuses for its lower-level managerial personnel. The policy’s key factor is a subjective judgment of “contribution to corporate goals.” A ...Provide the rejection region for the paired t test for each of the following sets of hypotheses: a. H0: μd = 0 versus Ha: μd ≠ 0 with n = 19, and α = .05 b. H0: μd ≤ 0 versus Ha: μd > 0 with n = 8, and α = ...Post your question