In an experiment to determine the best conditions to produce suitable crystals for the recovery and purification

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In an experiment to determine the best conditions to produce suitable crystals for the recovery and purification of biological molecules such as enzymes and proteins, crystals had appeared within 24 hours in 27 out of 60 trials of a particular solution without seed crystals, and had appeared within 24 hours in 36 out of 60 trials of a particular solution with seed crystals. Construct a one-sided confidence interval and calculate a one-sided p-value to investigate the evidence that the presence of seed crystals increases the probability of crystallization within 24 hours using this method?
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