Question

In screening for compounds useful in treating hypertension ( high blood pressure), ­researchers assign six rats to each of three groups. The rats in group 1 receive .1 mg/ kg of a test compound; those in groups 2 and 3 receive .2 and .4 mg/ kg, respectively. The response of interest is the decrease in blood pressure 2 hours postdose compared to the corresponding predose blood pressure. The data are shown here:
a. Fit the following model to the data.
b. Use residual plots to examine the fit to the model in part (a).
c. Conduct a statistical test of H0: β1 ≤ 0 versus Ha: β1 > 0. Give the p-value for your test.


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  • CreatedNovember 21, 2015
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