In step 7 of fatty-acid biosynthesis (Figure), dehydration of a ?-hydroxy thioester occurs to give trans-crotonyl ACP.
Question:
In step 7 of fatty-acid biosynthesis (Figure), dehydration of a ?-hydroxy thioester occurs to give trans-crotonyl ACP. Is the dehydration a syn elimination or an anti elimination?
Transcribed Image Text:
CH3ČSCOA Acetyl CoA O An acetyl group is HSACP HCOS", ATP O Acetyl CoA is carboxylated to give malonyl CoA. transferred from CoA to HSCOA ADP + P + H ACP (acyl carrior protein). DČCH2ČSCOA CH3CSACP Acetyl ACP Malonyl CoA 8 The acetyl group is transferred again, from ACP to a synthase enzyme. O The malonyl group is HS-Synthase HSACP transferred from CoA to ACP. HSACP HSCOA -оссн,сsACP CH3CS-Synthase Acetyl synthase Malonyl ACP 6 Claisen-like condensation of malonyl ACP with acetyl synthase occurs, followed by decarboxylation to yield acetoacetyl ACP, a B-keto S-Synthuse + CO2 thioester. CHасснCSACP Acetoacetyl ACP NADPHH O Reduction of the ketone by NADPH yields the corresponding 8-hydroxy NADP thioester. OH CHяCн сH,CSACP B-Hydroxybutyryl ACP O Dehydration of B-hydroxybutyryl ACP gives crotonyl ACP, an aB-unsaturated thioester. CH3CH=CHCSACP Crotonyl ACP NADPH/H O Reduction of the double NADP+ bond yields the saturated, chain elongated butyryl ACP. CH3CH2CH2ČSACP Butyryl ACP H20 HgC SACP H3C SACP нн trans-Crotonyl ACP
Fantastic news! We've Found the answer you've been seeking!
Step by Step Answer:
Answer rating: 84% (13 reviews)
If dehydration removes the proR hydr...View the full answer
Answered By
Ashington Waweru
I am a lecturer, research writer and also a qualified financial analyst and accountant. I am qualified and articulate in many disciplines including English, Accounting, Finance, Quantitative spreadsheet analysis, Economics, and Statistics. I am an expert with sixteen years of experience in online industry-related work. I have a master's in business administration and a bachelor’s degree in education, accounting, and economics options.
I am a writer and proofreading expert with sixteen years of experience in online writing, proofreading, and text editing. I have vast knowledge and experience in writing techniques and styles such as APA, ASA, MLA, Chicago, Turabian, IEEE, and many others.
I am also an online blogger and research writer with sixteen years of writing and proofreading articles and reports. I have written many scripts and articles for blogs, and I also specialize in search engine
I have sixteen years of experience in Excel data entry, Excel data analysis, R-studio quantitative analysis, SPSS quantitative analysis, research writing, and proofreading articles and reports. I will deliver the highest quality online and offline Excel, R, SPSS, and other spreadsheet solutions within your operational deadlines. I have also compiled many original Excel quantitative and text spreadsheets which solve client’s problems in my research writing career.
I have extensive enterprise resource planning accounting, financial modeling, financial reporting, and company analysis: customer relationship management, enterprise resource planning, financial accounting projects, and corporate finance.
I am articulate in psychology, engineering, nursing, counseling, project management, accounting, finance, quantitative spreadsheet analysis, statistical and economic analysis, among many other industry fields and academic disciplines. I work to solve problems and provide accurate and credible solutions and research reports in all industries in the global economy.
I have taught and conducted masters and Ph.D. thesis research for specialists in Quantitative finance, Financial Accounting, Actuarial science, Macroeconomics, Microeconomics, Risk Management, Managerial Economics, Engineering Economics, Financial economics, Taxation and many other disciplines including water engineering, psychology, e-commerce, mechanical engineering, leadership and many others.
I have developed many courses on online websites like Teachable and Thinkific. I also developed an accounting reporting automation software project for Utafiti sacco located at ILRI Uthiru Kenya when I was working there in year 2001.
I am a mature, self-motivated worker who delivers high-quality, on-time reports which solve client’s problems accurately.
I have written many academic and professional industry research papers and tutored many clients from college to university undergraduate, master's and Ph.D. students, and corporate professionals. I anticipate your hiring me.
I know I will deliver the highest quality work you will find anywhere to award me your project work. Please note that I am looking for a long-term work relationship with you. I look forward to you delivering the best service to you.
3.00+
2+ Reviews
10+ Question Solved
Related Book For
Question Posted:
Students also viewed these Organic Chemistry questions
-
What do you see in step 7 of the procedure?
-
In step 6 of fatty-acid biosynthesis (Figure), acetoacetyl ACP is reduced stereo specifically by NADPH to yield an alcohol. Does hydride ion add to the Si face or the Re face of acetoacetylACP?...
-
Give the mechanism for the last step in the biosynthesis of isopentenyl pyrophosphate, showing why ATP is required.
-
On January 1, 2021, Access IT Company exchanged $980,000 for 40 percent of the outstanding voting stock of Net Connect. Especially attractive to Access IT was a research project underway at Net...
-
Ergo Unlimited's current year's free cash flow is $10 million. It is projected to grow at 20% per year for the next five years. It is expected to grow at a more modest 5% beyond the fifth year. The...
-
A penny rides on top of a piston as it undergoes vertical simple harmonic motion with an amplitude of 4.0 cm. If the frequency is low, the penny rides up and down without difficulty. If the frequency...
-
Determine whether the following can be probability distributions of a random variable which can take on only the values \(1,2,3\), and 4 . (a) \(f(1)=0.19, \quad f(2)=0.27, \quad f(3)=0.27\), and...
-
St. Lukes Medical Center has a single operating room that is used by local physicians to perform surgical procedures. The cost of using the operating room is accumulated by each patient procedure and...
-
Create a transition table for the following DFA: 1 90 0 91 1 0 92 1
-
You are a lead auditor from ABC Auditors Pty Ltd. Your client is Cassey's Quality Cars Ltd who are a large car dealership with branches across Queensland. ABC Auditors have performed audits for past...
-
The initial reaction in Problem 29.42, conversion of two molecules of acetyl CoA to one molecule of acetoacetyl CoA, is a Claisen reaction. Assuming that there is a base present show the mechanism of...
-
In step of fatty-acid biosynthesis (Figure), reduction of Trans-crotonyl ACP gives butyryl ACP. A hydride from NADPH adds to C3 of the crotonyl group from the Re face, and Protonation on C2 occurs on...
-
Suppose that you are interested in buying yourself a new computer. Create a cost-benefit analysis that illustrates the return on investment that you would receive from making this purchase....
-
What is the purpose of a performance improvement plan (PIP) in performance management?
-
Write a Research Essay that analyzes a specific idea within a broader topic, with factual evidence and academic sources to back up your interpretation/thesis. Making sure that you have a specific...
-
Question THREE A had four million ordinary shares in issue and ranking for dividend at 1 January 2023. On 30 September, one million further shares were issued. Earnings for the year ended 31 December...
-
Starting next year you plan on saving for a trip 10 years from now. You plan to save a $1000 a year from year 1 to year 9 because in year 10 there is no point in putting money away if you are going...
-
Company A has issued a bond with a face value of $1,000 and a coupon rate of 5%. The bond matures in 5 years and has a yield to maturity of 6%. 1. What is a bond and how is it different from stocks?...
-
Find the \(1-\Omega\) energy carried by the signal \(F(\omega)=25 /\left(\omega^{2}ight.\) \(+625)\).
-
on 8 For the following set of lengths 130, 170, 160, 160, 150, 190 Third quartile is: et red d out of Select one: O a. 160 a question O b. 145 O c. 175 O d. 180
-
If octane is burned in a closed, constant volume reactor with 20% excess air, what is the maximum amount of shaft work that can be produced?
-
The reaction of thiocyanogen (NPCS±SCPN) with cis-cyclooctene proceeds by anti addition. A bridged sulfonium ion is presumed to be an intermediate. Write a stepwise mechanism for this...
-
On the basis of the mechanism of cationic polymerization, predict the alkenes of molecular formula C12H24 that can most reasonably be formed when 2-methylpropene [(CH3)2C=CH2] is treated with...
-
On being heated with a solution of sodium ethoxide in ethanol, compound A (C7H15Br) yielded a mixture of two alkenes B and C, each having the molecular formula C7H14. Catalytic hydrogenation of the...
-
Can Bitcoin Be a National Currency? El Salvador Is Trying to Find Out. - WSJ https://www.wsj.com/articles/bitcoin-national-currency-el-salvador-11645026831 1. El Salvador adopted Bitcoin as a...
-
Income Statement and Balance Sheet On March 1, Amy Dart began Dart Delivery Service, which provides delivery of bulk mailings to the post office neighborhood delivery of weekly newspapers, data...
-
How does the foundational article written by Brandeis and Warren in 1890 (The Right to Privacy) influence health information privacy policy and law in the United State today? R Brandeis and Warren,...
Study smarter with the SolutionInn App