MatheMatical Sketch a titration curve for aspartic acid, and indicate the pKa values of all titratable groups. Also indicate the pH range in which the conjugate acid–base pair +1 Asp and 0 Asp will act as a buffer.
Answer to relevant QuestionsWrite equations to show the ionic dissociation reactions of the following amino acids: aspartic acid, valine, histidine, serine, and lysine. Can a peptide act as a buffer? If so, why? MatheMatical Predict the predominant ionized forms of the following amino acids at pH 7: glutamic acid, leucine, threonine, histidine, and arginine. Theoretically, a protein could assume a virtually infinite number of configurations and conformations. Suggest several features of proteins that drastically limit the actual number. What is the effect of the altered amino acid sequence in Hb S that causes the cells to form sickle shapes?
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