One of the steps in the biosynthesis of uridine mono phosphate is the reaction of aspartate with

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One of the steps in the biosynthesis of uridine mono phosphate is the reaction of aspartate with carbamoyl phosphate to give carbamoyl aspartate followed by Cyclization to form dihydroorotate. Propose mechanisms for bothsteps.

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Organic Chemistry

ISBN: 9780495112587

7 Edition

Authors: John McMurry

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Question Posted: Mar 09, 2011 10:26 PM

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One of the steps in the biosynthesis of uridine mono phosphate is the reaction of aspartate with

Question:

H2N OPO,2- Carbamoyl phosphate н. P, Н2о H2N -H- —н н со N. Co2- Н N- Coz cO2 HạN Carbamoyl aspartate Dihydroorotate Aspartate

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Both steps are nucleophilic acyl s...View the full answer

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