Polymorphism implies that each different MHC protein binds a different peptide motif. However, for the MHC class I proteins, only 6 peptide motifs can be recognized in an individual, whereas over 6000 motifs can be recognized by the entire human population. What advantage does recognition of multiple motifs have for the individual? What potential advantage does recognition of the extremely large number of motifs have for the population? Can everyone process and present the same antigens?
Answer to relevant QuestionsAlthough genetic recombination events are important for generating significant diversity in the antigen-binding site of Igs, post-recombination somatic events may be even more important in achieving overall Ig diversity. Do ...Distinguish between the modes of action of three of the protein synthesis–inhibiting antibiotics. Differentiate between selective and differential media. Is eosin–methylene blue agar a selective medium or a differential medium? How and why is it used in a clinical laboratory? Distinguish between acute and chronic, mortality and morbidity, prevalence and incidence, and epidemic and pandemic, as these terms relate to infectious disease. Identify the major risk factors for acquiring human immunodeficiency virus (HIV) infection in the United States. Does this pattern hold for other geographic regions?
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