A nonsense codon can be suppressed. Suppression is a mutation at an unlinked site that restores wild-type function at the mutant site without changing the original mutation. Suppression of nonsense mutations was found to alter the structures of particular tRNAs. Consider a nonsense mutation resulting from alteration of a trp codon and identify a specific mutation in a tRNAencoding gene that could result in translation of the nonsense codon.