Consider the 10 region sequences for the bacterial promoters in Figure 24.6. Why is the consensus sequence
Question:
Consider the –10 region sequences for the bacterial promoters in Figure 24.6. Why is the consensus sequence more active in promoting transcription than any of the sequences associated with actual promoters?
Figure 24.6.
Transcribed Image Text:
Promoter for: trp operon G TTGACA tRNATyr AP2 lac operon recA lexA T7A3 -35 region CONSENSUS GTTGACA C TTTACA N16 Spacer N₁7 G TTCCAA CTTTACA N17 N17 CTTGATA N16 TTGACA N17 GTTGACA N17 -10 region TTAACT Spacer N₂ A TATGAT N₁ A GATACT N6 G TATGTT N6 ΤΑΤΑΑΤ N7 A TATACT No A TATAAT TACGAT N₁ A Transcribed Transcription start sites
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Biochemistry Concepts And Connections
ISBN: 9780134641621
2nd Edition
Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews
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