Propose a mechanism for the TPP-dependent step in isoleucine biosynthesis (see Figure 18.20). Draw the predicted product
Question:
Propose a mechanism for the TPP-dependent step in isoleucine biosynthesis (see Figure 18.20). Draw the predicted product of this reaction.
Figure 18.20.
Transcribed Image Text:
Isoleucine Threonine Serine-threonine PLP dehydratase NH3 CH-CH₂-C-coo a-Ketobutyrate OH Isoleucine CH₂-C-COO- Pyruvate -CH₂-CH-TPP Vallne Vallne Leucine Leucine
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Biochemistry Concepts And Connections
ISBN: 9780134641621
2nd Edition
Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews
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