Recent data indicate, as mentioned in the text, that the signal for eukaryotic mismatch repair, for identifying

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Recent data indicate, as mentioned in the text, that the signal for eukaryotic mismatch repair, for identifying the strand to be repaired, is incorporated ribonucleotides that have not yet been replaced by deoxyribonucleotides. Previous studies implicated nicks in the most recently synthesized DNA as the signal identifying the strand to be repaired. If DNA nicks comprise the signal, would you expect the nicked strand or the intact strand to be the strand to be repaired? Briefly explain your answer.

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Biochemistry Concepts And Connections

ISBN: 9780134641621

2nd Edition

Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews

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