Table 18.3 reports that the overall or pooled 95% CI for the RR across the four trials for stopping smoking in the MI group compared to the no treatment control group is 0.63 to 1.12.

Which, if any, of the following statements is CORRECT?

A. The above 95% CI definitely contains the true population RR for stopping smoking in the MI group compared to the no treatment control group.

B. The 95% CI is calculated as ±3 standard errors away from the mean difference.

C. There is a probability of 0.95 that the population RR for stopping smoking in the MI group compared to the no treatment control group lies between 0.63 and 1.12.

D. The 95% CI does not contain the true population RR for stopping smoking in the MI group compared to the no treatment control group.

E. The above 95% CI is likely to contain the true population RR for stopping smoking in the MI group compared to the no treatment control group.

Table 18.3

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MI No treatment 95% CI Study n N n N Weight RR Lower Upper 1 3 284 31 4.2 0.83 0.2 3.39 2 48 235 49 199 67.3 0.83 0.58 1.18 34 3 3 27 0 28 1 7.25 0.39 134.07 19 77 18 59 27.5 XXXX 0.47 1.4 Total 73 367 71 317 100 0.84 0.63 1.12 Heterogeneity chi-squared = 2.16 (df = YYYY) P = 0.54. I (variation in RR attributable to heterogeneity) = 0% Estimate of between-study variance tau-squared = 0. Test for overall effect: Z = 1.18, p = 0.24.