Table 6.4 reports that the 95% CI for the comparison of mean corn size at 12 months between the corn plaster and scalpel groups is: −1.7 to −0.2 mm. The research literature suggests that a difference or change in corn size of 1 mm or more would be regarded as clinically or practically important. Therefore the 95% CI shows that the difference in mean corn size at 12 months between the corn plaster and scalpel groups is:

A. Statistically significant and potentially clinically important.

B. Statistically significant and not clinically important.

C. Statistically significant and clinically important.

D. Not statistically significant but potentially clinically important.

E. Not statistically significant and not clinically important.

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Table 6.4 Index corn size, in millimetres, over time by group. Corn plaster Scalpel Size of (n = index (n = Mean 101) 101) 95% CI corn Mean SD Mean SD Difference Lower Upper P-value (mm) Baseline 3.9 (1.7) 3.8 (1.8) 3 1.7 (1.5) 2.7 (2.3) -1.0 -1.5 -0.5 months 6 1.7 (1.6) 2.4 (2.2) -0.7 -1.2 -0.2 months 9 1.7 (1.6) 2.2 (2.1) -0.5 -1.2 0.1 months 12 1.3 (1.6) 2.3 (2.2) -1.0 -1.7 -0.2 0.010 months