Various methods have been developed in order to increase the throughput in electrophoresis. Most of these designs vary in the flow arrangement and the changes in the direction of the electric field. These include the Philpot design, Hanning design, annular design, and rotating annular column, among many others. Discuss these arrangements. A comparison of the performance analysis has been done by Yoshisato et al. (1986), who used the well-studied glycineglutamic-acid solute pair as a model system. Study this and related papers and do a case study on performance analysis of various designs.