Sickle-cell anemia is caused by a genetic defect that substitutes valine for glutamic acid at one position
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Sickle-cell anemia is caused by a genetic defect that substitutes valine for glutamic acid at one position in two of the four chains of the hemoglobin protein. The result is a decrease in the water solubility of hemoglobin. Examine the structures of valine and glutamic acid and explain why this occurs.
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Valine and glutamic acid are both amino acids and they differ in their chemical structures particula...View the full answer
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