Cisplatin [cis-diamminedichloroplatinum(II)] is a potent treatment for certain types of cancers, but the trans isomer is not

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Cisplatin [cis-diamminedichloroplatinum(II)] is a potent treatment for certain types of cancers, but the trans isomer is not effective. What is the equilibrium constant at 298 K for the transformation of the cis to the trans isomer? Which is the favored isomer at 298 K, the cis or the trans isomer?Compound Cis-Pt (NH3)2Cl2 Trans-Pt(NH3)2Cl2 A H AfG (kJ/mol,298 K) (kJ/mol, 298 K) -467.4 -480.3 -228.7 -222.8

HN HN Pt CL CL cis isomer HN CL trans isomer CL Pt NH3

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Related Book For  answer-question

Chemistry And Chemical Reactivity

ISBN: 9780357001172

10th Edition

Authors: John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

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