A particular type of Drosophila mutant becomes paralyzed when the temperature is raised. The mutation affects the

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A particular type of Drosophila mutant becomes paralyzed when the temperature is raised. The mutation affects the structure of dynamin, causing it to be inactivated at a higher temperature. Indeed, the function of dynamin was discovered by analyzing the defect in these mutant fruit flies. The complete paralysis at the elevated temperature suggests that synaptic transmission between nerve and muscle cells is blocked. Suggest why signal transmission at a synapse might require dynamin.

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Essential Cell Biology

ISBN: 9780393680362

5th Edition

Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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