A. Predict the membrane orientation of a protein that is synthesized with an un cleaved, internal signal
Question:
A. Predict the membrane orientation of a protein that is synthesized with an un cleaved, internal signal sequence (shown as the red start-transfer sequence in Figure 15–17) but does not contain a stop-transfer sequence.
B. Similarly, predict the membrane orientation of a protein that is synthesized with an N-terminal cleaved signal sequence followed by a stop-transfer sequence, followed by a start-transfer sequence.
C. What arrangement of signal sequences would enable the insertion of a multipass protein with an odd number of transmembrane segments?
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A When a protein is synthesized with an uncleaved internal signal sequence starttransfer sequence but lacks a stoptransfer sequence it is likely to ad...View the full answer
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Essential Cell Biology
ISBN: 9780393680362
5th Edition
Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter
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