Remembering that the amino acid side chains projecting from each polypeptide backbone in a sheet point

Remembering that the amino acid side chains projecting from each polypeptide backbone in a β sheet point alternately above and below the plane of the sheet (see Figure 4−13A), consider the following protein sequence: Leu-Lys-Val-Asp-Ile-Ser-Leu-Arg-Leu-Lys-Ile-Arg-Phe-Glu. Do you find anything remarkable about the arrangement of the amino acids in this sequence when incorporated into a β sheet? Can you make any predictions as to how the β sheet might be arranged in a protein?

Figure 4-13(A)

Transcribed Image Text:

(A) ß sheet R R R R R R oxygen R peptide bond R R R nitrogen R Onn R R carbon carbon hydrogen R hydrogen bond amino acid side chain