Susans grandfather was deaf, and passed down a hereditary form of deafness within Susans family as shown

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Susan’s grandfather was deaf, and passed down a hereditary form of deafness within Susan’s family as shown in Figure Q19–12.

A. Is this mutation most likely to be dominant or recessive?

B. Is it carried on a sex chromosome? Why or why not?

C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected and 7 unaffected). In comparing these 11 SNP results, how long a haplotype block would you expect to find around the critical gene? How might you detect it?


Figure Q19–12image

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Essential Cell Biology

ISBN: 9780393680362

5th Edition

Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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