J.B. has Parkinson disease that has been controlled for several years with levodopa. After he begins a

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J.B. has Parkinson disease that has been controlled for several years with levodopa. After he begins a health food regimen with lots of vitamin B6, his tremors return, and he develops a rapid heart rate, hypertension, and anxiety. The nurse investigating the problem discovers that vitamin B6 can speed the conversion of levodopa to dopamine in the periphery, leading to these problems. The nurse would consider this problem.

a. A drug–laboratory test interaction. 

b. A drug–drug interaction. 

c. An accumulation effect. 

d. A sensitivity reaction.

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