The nurse instructs the patient to use care when applying topical antifungal agents to prevent systemic absorption

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The nurse instructs the patient to use care when applying topical antifungal agents to prevent systemic absorption because 

a. The fungus is only on the surface. 

b. These drugs are too toxic to be given systemically. 

c. Absorption would prevent drug effectiveness. 

d. These drugs can cause serious local burning and pain.

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