A bacterial chromosome consists of a proteinDNA complex in which its single DNA molecule appears to be

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A bacterial chromosome consists of a protein–DNA complex in which its single DNA molecule appears to be supercoiled. However, in contrast to the case with naked circular duplex DNA, the light singlestrand nicking of chromosomal DNA does not abolish this supercoiling. What does this indicate about the structure of the bacterial chromosome, that is, how do its proteins constrain its DNA?

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Fundamentals Of Biochemistry Life At The Molecular Level

ISBN: 9781118918401

5th Edition

Authors: Donald Voet, Judith G Voet, Charlotte W Pratt

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