The nucleotide deoxyuridylate (dUMP) is converted to deoxythymidylate (dTMP) by methylation. Could this explain why rapidly dividing

Question:

The nucleotide deoxyuridylate (dUMP) is converted to deoxythymidylate (dTMP) by methylation. Could this explain why rapidly dividing cancer cells consume large quantities of glycine?

Fantastic news! We've Found the answer you've been seeking!

Step by Step Answer:

Related Book For book-img-for-question

Fundamentals Of Biochemistry Life At The Molecular Level

ISBN: 9781118918401

5th Edition

Authors: Donald Voet, Judith G Voet, Charlotte W Pratt

See More Books

Question Posted: Oct 08, 2023 01:11 AM

See More Questions

Consider a Markov process with two states and transition probability matrix [3/4 1/4] P = [1/2 1/2] (a) Draw a Markov chain showing two states and the transition probabilities. (b) Find the...
From a management perspective, formulate and explain your company's offensive or defensive strategy to improve its market position in the next 3 years. Explain whether your company will be a first...
Cancer cells grow so rapidly that they have a higher rate of anaerobic metabolism than most body tissues, especially at the center of a tumor. Can you use drugs that poison the enzymes of anaerobic...
Court Casuals has 100,000 shares of common stock outstanding as of the beginning of the year and has the following transactions affecting stockholders' equity during the year. May 18 Issues 25,000...
What drove Microsofts decision to enter the industry with its Xbox offering? In 1968, Nolan Bushell, the 24-year-old son of a Utah cement contractor, graduated from the University of Utah with a...
Collins Computer Timeshare Company SA entered into the following transactions during May 2017. 1. Purchased computer terminals for R$20,000 from Digital Equipment on account. 2. Paid R$3,000 cash for...
Set up the equations for predicting the averaged isotropic shear modulus of a randomly oriented short-fiber composite. Your answer should be in terms of the fiber and matrix properties and volume...
Everybody knew Ed McAlister was a brilliant businessman. He had taken a small garbage collection company in Kentucky and built it up to be one of the largest and most profitable waste management...
A glass window is 2.0 m wide and 1.5 m high and 7.5 mm thick. The temperature of the inner surface is 18 C and that of the outer surface is 11 C. (a) Find the rate of heat flow through the window....
Proliferating cells require NADPH for biosynthetic processes. Much of the NADPH is provided by the pentose phosphate pathway, but 10-formyl tetrahydrofolate is also a source of reducing power....
Nitrosomonas is a photophobic (light-avoiding) chemoautotrophic bacterium that converts ammonia into nitrite. Explain how the organism can fix CO 2 via the Calvin cycle in the absence of sunlight.
A machine at Kasem Steel Corporation makes iron rods that are supposed to be 50 inches long. However, the machine does not make all rods of exactly the same length. It is known that the probability...
A beam AB of span 1 2 m is simply supported at its ends is subjected to a point load of 4 0 kN at C at a distance of 4 m from left end. Using moment area method, Compute thedeflection at the point C...
It might be a good idea to buy a mobile home to use while you are going to school. Suppose you live in the mobile home for four years, but your roommate also pays you $3,000 a year, paid to you at...
Frank owns a $ 5 0 0 , 0 0 0 life insurance policy on his wife Tonya. Frank's son, Sam, is designated as the beneficiary of the policy. Within 9 M of Tonya's death, Sam disclaims his interest in the...
A lump of iron of mass 5 . 6 4 3 kg is suspended ( completely immersed ) in a brine solution of density 1 0 8 5 kg m - 3 The volume of the iron is 0 . 0 0 0 7 1 7 m 3 . Calculate the upthrust on the...
What does the following code print? int x = 5; while (x > 10) } x++; System.out.print (x + " ");
a. On July 1, 2015, Lopez Company paid $1,200 for six months of insurance coverage. No adjustments have been made to the Prepaid Insurance account, and it is now December 31, 2015. Prepare the...
Evenflow Power Co. is considering a new project that is a little riskier than the current operations of the company. Thus, management has decided to add an additional 1.5% to the company's overall...
A 0.1429 g sample of sucrose, C 12 H 22 O 11 , is burned in a bomb calorimeter. In order to produce the same temperature rise in the calorimeter as the reaction, 2353 J must be expended. a. Calculate...
Identify whether you would use dilute sulfuric acid or concentrated sulfuric acid to achieve each of the following transformations. In each case, explain your choice. a. b. [H,SO,] - . [H,SO,] + H20
Under anaerobic conditions, glucose is broken down in muscle tissue to form lactic acid according to the reaction: C 6 H 12 O 6 (s) 2CH 3 CHOHCOOH(s). Thermodynamic data at T = 298 K for glucose and...
Given two distributions, fo = N(0, 1), f = N(0.5, 1) (meaning that we are interested in detecting a mean shift of minimum size 3), derive what should be the CUSUM statistic (i.e., write down the CUSM...
A multiple linear regression model is fit to a data set of 20 observations, giving =7+8X1+6X2+14X3. a.) If SSE 31, calculate MSE= b.) If in addition, the estimated standard error of is 3.9, calculate...
1 IF F(x) = x- 6/x Find the Following. (Give Exact answers. Do not rond.) A F (2) B F(-2) IFK(X) = (3 IFXCO X+6 IFOX <1, find the following \1-X IF X1 (K(-6) K(1) K(-0.007) (6) K (0) (0) F(9) IF...

The nucleotide deoxyuridylate (dUMP) is converted to deoxythymidylate (dTMP) by methylation. Could this explain why rapidly dividing

Question:

Step by Step Answer:

Yes the conversion of deoxyuridylate dUMP to deoxythymidylate dTMP through methylation is indeed linked to the consumption of glycine especially in ra...View the full answer

Fundamentals Of Biochemistry Life At The Molecular Level

Students also viewed these Sciences questions