Under cellular conditions, dATP can be oxidized to its 2-hydroxy form, which is a substrate for an

Question:

Under cellular conditions, dATP can be oxidized to its 2-hydroxy form, which is a substrate for an enzyme that converts 2-OH-dATP to 2-OH-dAMP + PPi. Explain why compounds that inhibit the activity of this enzyme would be effective anticancer agents. 

Fantastic news! We've Found the answer you've been seeking!

Step by Step Answer:

Related Book For  book-img-for-question

Fundamentals Of Biochemistry Life At The Molecular Level

ISBN: 9781118918401

5th Edition

Authors: Donald Voet, Judith G Voet, Charlotte W Pratt

Question Posted: