Consider a woman whose brother is afflicted with hemophilia, which implies that the womans mother has the

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Consider a woman whose brother is afflicted with hemophilia, which implies that the woman’s mother has the hemophilia gene on one of her two X chromosomes (almost surely not both, since that is generally fatal). Thus there is a 50–50 chance that the woman’s mother has passed on the bad gene to her. The woman has two sons, each of whom will independently inherit the gene from one of her two chromosomes. If the woman herself has a bad gene, there is a 50–50 chance she will pass this on to a son. Suppose that neither of her two sons is afflicted with hemophilia. What then is the probability that the woman is indeed the carrier of the hemophilia gene? What is this probability if she has a third son who is also not afflicted?

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Modern Mathematical Statistics With Applications

ISBN: 9783030551551

3rd Edition

Authors: Jay L. Devore, Kenneth N. Berk, Matthew A. Carlton

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