A mutation in the Ras protein renders Ras constitutively active (Ras D ). What is constitutive activation?
Question:
A mutation in the Ras protein renders Ras constitutively active (RasD). What is constitutive activation? How is constitutively active Ras cancer promoting? What type of mutation might render the following proteins constitutively active:
(a) Smad3
(b) MAP kinase
(c) Nf-KB?
Fantastic news! We've Found the answer you've been seeking!
Step by Step Answer:
Answer rating: 100% (10 reviews)
Constitutive activation is the alteration of a protein or signaling pathway such that it is function...View the full answer
Answered By
Pushpinder Singh
Currently, I am PhD scholar with Indian Statistical problem, working in applied statistics and real life data problems. I have done several projects in Statistics especially Time Series data analysis, Regression Techniques.
I am Master in Statistics from Indian Institute of Technology, Kanpur.
I have been teaching students for various University entrance exams and passing grades in Graduation and Post-Graduation.I have expertise in solving problems in Statistics for more than 2 years now.I am a subject expert in Statistics with Assignmentpedia.com.
4.40+
3+ Reviews
10+ Question Solved
Related Book For
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
Question Posted:
Students also viewed these Life Sciences questions
-
You are a summer intern in a clinical hematology lab. The lab director gives you a sample of a patient's blood proteins and asks you to characterize the thrombin in the sample. She also tells you...
-
Lets suppose a mutation in the glucocorticoid receptor does not prevent the binding of the glucocorticoid hormone to the protein but prevents the ability of the receptor to activate transcription....
-
Let's suppose a person is homozygous for a mutation in the IRP gene that changed the structure of the iron regulatory protein in such a way that it could not bind iron, but it could still bind to...
-
Bill and Mary are married. Mega Corporation employs them both. In 2018, Mary earned $70,000 and Bill earned $135,000, in both cases W-2 wages. How much FICA tax were they required to pay for 2018?
-
A manufacturer is evaluating options regarding his production equipment. He is trying to decide whether he should refurbish his old equipment for $70,000, make major modifications to the production...
-
Haverhill Engineers Ltd manufactures components for the car industry. It is considering automating its line for producing crankshaft bearings. The automated equipment will cost 700,000. It will...
-
Discuss some of the key environmental challenges facing the world and the differences between pollution in wealthy and poor nations.
-
Capri Wigs Company supplies wigs and hair care products to beauty salons throughout California and the Pacific Northwest. The accounts receivable clerk for Capri Wigs prepared the following partially...
-
What is the solution to this system of equations? 3x + 7y = 18 3x-4y=-48
-
The following financial statements and additional information are reported. Assets Cash IKIBAN INC. Comparative Balance Sheets June 30, 2019 and 2018 Accounts receivable, net. Inventory Prepaid...
-
Once an activated signaling pathway has elicited the proper changes in target gene expression, the pathway must be inactivated. Otherwise, pathologic consequences may result, as exemplified by...
-
The enzyme Stell participates in several distinct MAP kinase signaling pathways in the budding yeast S. cerevisiae. What is the substrate for Ste 11 in the mating factor signaling pathway? When a...
-
At January 1, 2018, Youngstown Limited reported the following property, plant, and equipment accounts: Accumulated depreciation-buildings ..........................$ 62,200,000 Accumulated...
-
1. A supernet has a first address of 205.17.64.0 and a supernet mask of 255.255.224.0. a. How many blocks are in this supernet and what is the range of addresses of each block? (15 points) b. A...
-
Consider the grammar below: G=({S,A,B),(a,b,c},S,P) S ScS aSS | aA | Bb AaAla BBb|A a) Write the leftmost derivation for the string aacabb b) Write the rightmost derivation for the string aacabb
-
A derangement is a permutation in which no element appears in its original position. Give a combi- natorial proof that: n! = =(") do + (") d + (2) dz + ... + (") da, where d, is the number of...
-
Timers can generate certain interrupts, so-called overflow and compare match interrupt. Since timer is a peripheral, it can be activated in AVR register. Supposed we need to flash a LED every 100 ms...
-
3. The following structure will be made with round aluminum rods with E-68 GPa and v=0.28. The applied forces Fx and Fy are equal to 3 and 5 kN, respectively. Z 1m X Fx A B Fy 2m C a) Point A will...
-
At what point(s) on the curve x = 3t 2 + 1, y = t 3 - 1 does the tangent line have slope 1/2?
-
Havel says the grocer doesnt believe what is on the sign and indeed, he says the grocers customers will barely notice it. But Havel maintains that the sign serves a specific function. How would you...
-
The photosystems responsible for absorption of light energy are each composed of two linked components, the reaction center and an antenna complex. What is the pigment composition and role of each...
-
Photosynthesis in green and purple bacteria does not produce O 2 . Why? How can these organisms still use photosynthesis to produce ATP? What molecules serve as electron donors in these organisms?
-
Chloroplasts contain two photosystems. What is the function of each? For linear electron flow, diagram the flow of electrons from photon absorption to NADPH formation. What does the energy stored in...
-
Consider the Obsidian Project, which requires an investment of $362,868 initially, with subsequent cash flows of $58,160, $72,091 and $97,900. We can characterize the project with the following...
-
1. Define human resource (HR) management and explain how it relates to the management process. Cite examples of the application of these concepts, preferably from personal, professional experience.
-
Mickley Corporation produces two products, Alpha6s and Zeta7s, which pass through two operations, Sintering and Finishing. Each of the products uses two raw materialsX442 and Y661. The company uses a...
Study smarter with the SolutionInn App