Ammonia (NH 3 ) is a weak base that under acidic conditions becomes protonated to the ammonium ion in the following reaction NH 3 H NH4 NH 3 freely permeates biological membranes, including those of lysosomes The lysosome is a sub cellular organelle with a pH of about 4 5 5 0 the pH of cytoplasm is...

In the acidic pH of a lysosome ammonia is converted to ammonium ion Ammonium ion is ...

Ammonia (NH 3 ) is a weak base that under acidic conditions becomes protonated to the ammonium

Question:

Ammonia (NH₃) is a weak base that under acidic conditions becomes protonated to the ammonium ion in the following reaction:

NH₃ + H⁺ → NH4⁺

NH₃freely permeates biological membranes, including those of lysosomes. The lysosome is a sub-cellular organelle with a pH of about 4.5-5.0; the pH of cytoplasm is - 7.0. What is the effect on the pH of the fluid content of lysosomes when cells are exposed to ammonia? Protonated ammonia does not diffuse freely across membranes.