Explain how expression of a dominant-negative mutant of JAK blocks the erythropoietin (Epo) cytokine signaling pathway.
Question:
Explain how expression of a dominant-negative mutant of JAK blocks the erythropoietin (Epo) cytokine signaling pathway.
Fantastic news! We've Found the answer you've been seeking!
Step by Step Answer:
Answer rating: 87% (8 reviews)
A dominantnegative mutant of JA...View the full answer
Answered By
Somshukla Chakraborty
I have a teaching experience of more than 4 years by now in diverse subjects like History,Geography,Political Science,Sociology,Business Enterprise,Economics,Environmental Management etc.I teach students from classes 9-12 and undergraduate students.I boards I handle are IB,IGCSE, state boards,ICSE, CBSE.I am passionate about teaching.Full satisfaction of the students is my main goal.
I have completed my graduation and master's in history from Jadavpur University Kolkata,India in 2012 and I have completed my B.Ed from the same University in 2013. I have taught in a reputed school of Kolkata (subjects-History,Geography,Civics,Political Science) from 2014-2016.I worked as a guest lecturer of history in a college of Kolkata for 2 years teaching students of 1st ,2nd and 3rd year. I taught Ancient and Modern Indian history there.I have taught in another school in Mohali,Punjab teaching students from classes 9-12.Presently I am working as an online tutor with concept tutors,Bangalore,India(Carve Niche Pvt.Ltd.) for the last 1year and also have been appointed as an online history tutor by Course Hero(California,U.S) and Vidyalai.com(Chennai,India).
4.00+
2+ Reviews
10+ Question Solved
Related Book For
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
Question Posted:
Students also viewed these Life Sciences questions
-
A mutant strain has a defective lac operator site that results in the constitutive expression of the lac operon. Outline an experiment you would carry out to demonstrate that the operator site must...
-
1. G. Johnson and colleagues have analyzed the MAP kinase cascade in which MEKK2 participates in mammalian cells. By a yeast two-hybrid screen (see Chapter 7), MEKK2 was found to bind MEK5, which can...
-
Explain how epigenetics is related to the expression: phenotype = genotype + environment.
-
Consider a process consisting of five resources that are operated eight hours per day. The process works on three different products, A, B, and C; Resource Number of Workers Processing Time for A...
-
Appraise and evaluate what are the critical economic imperatives managers must consider in the selection of a global strategy including financial implications affecting profitability of the...
-
Each unit in Problem 12.5 is initially operating at one-half its own rating when the load suddenly increases by 100 MW. Determine (a) the steadystate decrease in area frequency, and (b) the MW...
-
What important roles do children play in extremely impoverished communities?
-
The adjusted trial balance for Sharp Construction as of December 31, 2011, follows. J. Sharp invested $50,000 cash in the business during year 2011 (the December 31, 2010, credit balance of the J....
-
1. Show the starting materials and reagents you need to make the following epoxides? Try to use different reagents for both. a) b)
-
Alison and Chuck Renny began operations of their furniture repair shop (Lazy Sofa Furniture, Inc.) on January 1, 2017. The annual reporting period ends December 31. The trial balance on January 1,...
-
Erythropoietin (Epo) is a hormone that is produced naturally in the body in response to low O 2 levels in the blood. The intracellular events that occur in response to Epo binding to its cell surface...
-
Even though GRB2 lacks intrinsic enzymatic activity, it is an essential component of the epidermal growth factor (EGF) signaling pathway that activates MAP kinase. What is the function of GRB2? What...
-
Logan B. Taylor is a widower whose wife, Sara, died on June 6, 2011. He lives at 4680 Dogwood Lane, Springfield, MO 65801. He is employed as a paralegal by a local law firm. During 2013, he had the...
-
9) Mr. Barnes operates a power plant in the local market. Mr. Barnes' marginal cost function is: MC(q) = 2 + 0.1q. Mr. Barnes can sell all the output he produces for $9 per unit. (This means that the...
-
Glyde Air Fresheners is the price leader in the solid room aromatizer industry, which has a total market demand given by Q= 80 - 2P. Glyde has competition from a fringe of four small firms that...
-
It's now one year later. Your decision to stay open proved to be a good one-you had a loss last year, but it was not as much as you would have lost if you had shut down for the year. Your patience...
-
highlight all of these questions delivered in these bullet points. Be sure to provide lots of detail as well. What is Kroger Delivery? Importance of Kroger Delivery in the grocery industry? Overview...
-
Directions: Read the newsletter Credit Cards. Complete the activities in the newsletter. These activities will not be submitted for grading. http://www.ogburn.org/PFLesson11.pdf Research and describe...
-
Find the area of the region enclosed by the astroid x = a cos 3 , y = a sin 3 . (Astroids are explored in the Laboratory Project on page 649.) a
-
On April 29, 2015, Auk Corporation acquires 100% of the outstanding stock of Amazon Corporation (E & P of $750,000) for $1.2 million. Amazon has assets with a fair market value of $1.4 million (basis...
-
The electron transport chain consists of a number of multiprotein complexes, which work in conjunction to pass electrons from an electron carrier, like NADH, to O 2 . What is the role of these...
-
It is estimated that each electron pair donated by NADH leads to the synthesis of approximately three ATP molecules, whereas each electron pair donated by FADH 2 leads to the synthesis of...
-
Describe the main functions of the different components of ATP synthase enzyme in the mitochondrion. A structurally similar enzyme is responsible for the acidification of lysosomes and endosomes....
-
Time Value of Money calculations are a great way to figure out how much payments will be on loans or how much we need to save over time to achieve our financial goals. The calculation always uses the...
-
Dawson Toys, Limited, produces a toy called the Maze. The company has recently created a standard cost system to help control costs and has established the following standards for the Maze toy:...
-
Employer sponsored health care coverage create situation in which health insurers face high moral hazard. a. Graphically describe how health insurance creates this moral hazard. In your answer,...
Study smarter with the SolutionInn App