It was clear from the early days of studying development that certain morphogenetic substances were present in
Question:
It was clear from the early days of studying development that certain “morphogenetic” substances were present in the egg and segregated asymmetrically into cells of the developing embryo. One such investigation in ascidian (sea squirt) embryos examined endodermal alkaline phosphatase, which could be visualized by a histochemical stain. Treatment of embryos with cytochalasin B stopped cell division, but did not block expression of alkaline phosphatase at the appropriate time. Treatment with actinomycin D, which blocks transcription, did not interfere with expression of alkaline phosphatase. Treatment with puromycin, which blocks translation, eliminated expression of alkaline phosphatase. What is the likely nature of the morphogenetic substance that gives rise to alkaline phosphatase?
Step by Step Answer:
Molecular Biology Of The Cell
ISBN: 9780815344322
6th Edition
Authors: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter