The group in DNA that reacts with the diol-epoxide has the following general structure. Using mechanistic reasoning,
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The group in DNA that reacts with the diol-epoxide has the following general structure. Using mechanistic reasoning, show how the amino group indicated by the asterisk (*) might react with the epoxide group of the diol-epoxide in Eq. 16.50.
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benzo[a]pyrene living tissue (enzymes, O₂) HO" OH benzo[a]pyrene diol-epoxide (16.50)
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