The relationship between the melting T m and GC content can be expressed, in its much simplified

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The relationship between the melting Tm and GC content can be expressed, in its much simplified form, by the formula Tm = 69 + 0.41 (% GC).

(a) Calculate the melting temperature of E. coli DNA that has about 50% GC.

(b) Estimate the %GC of DNA from a human kidney cell where Tm = 85°C. 

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Principles of Genetics

ISBN: 978-1119142287

7th edition

Authors: D. Peter Snustad, Michael J. Simmons

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