1. The death-cap fungus Amanita phalloides contains a bicyclic octapeptide called amanitin, which is exceedingly poisonous in nature. This fungal toxin alpha amanitin inhibits eukaryotic RNA polymerases. The sensitivity of the three eukaryotic RNA polymerases to this toxin varies. Which of the following rankings (in descending order) most appropriately depicts sensitivity to alpha amanitin?

a. RNA POL II > RNA POL I > RNA POL III

b. RNA POL II > RNA POL III > RNA POL I

c. RNA POL I > RNA POL III > RNA POL II

d. RNA POL III > RNA POL II > RNA POL I

Answer rating: 100% (QA)

Solution The correct option is 1 b RNA POL II RNA POL III RNA POL I Amanita a genus of mushrooms tha... View the full answer