Insulin binding to an insulin receptor of a cell stimulates tyrosine kinase activity. However, an uncontrollably...
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Insulin binding to an insulin receptor of a cell stimulates tyrosine kinase activity. However, an uncontrollably high number of insulin-insulin receptor binding causes negative impacts on cellular viability. A researcher developed a new ligand X that can act as a scavenger of insulin by binding to an insulin receptor. Researchers find that if given enough time, 85% of insulin receptors form a complex with the ligand X. Consider that the initial concentration of the ligand X is 220mM and the dissociation constant is known to be 5.37 × 10-4 s-1, estimate how long it takes for half of the insulin receptors to form complexes with the ligand X Assume there is no insulin-insulin receptor complex and there is no insulin in the solution. Insulin binding to an insulin receptor of a cell stimulates tyrosine kinase activity. However, an uncontrollably high number of insulin-insulin receptor binding causes negative impacts on cellular viability. A researcher developed a new ligand X that can act as a scavenger of insulin by binding to an insulin receptor. Researchers find that if given enough time, 85% of insulin receptors form a complex with the ligand X. Consider that the initial concentration of the ligand X is 220mM and the dissociation constant is known to be 5.37 × 10-4 s-1, estimate how long it takes for half of the insulin receptors to form complexes with the ligand X Assume there is no insulin-insulin receptor complex and there is no insulin in the solution.
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Related Book For
Income Tax Fundamentals 2013
ISBN: 9781285586618
31st Edition
Authors: Gerald E. Whittenburg, Martha Altus Buller, Steven L Gill
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