A 5'8, 240 lb., 52-year-old project manager went in for a physical exam. His blood pressure...
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A 5'8", 240 lb., 52-year-old project manager went in for a physical exam. His blood pressure was > 180/115 on three separate days. Further examination showed normal to low plasma renin activity, elevated total peripheral resistance (TPR), cardiac output (CO) of 7.2 L/min, X-ray evidence of left ventricular hypertrophy, retinal hemorrhages, and mild polyuria. Recommended therapy included weight reduction to his ideal level, a low-salt diet (<2 gm/day sodium), prudent exercise, and a reduction in alcohol consumption (<3 oz whiskey/day). This change in lifestyle did little to change the condition. Medication was initiated in the form of an oral diuretic and progressed to a beta-blocker. Eventually a vasodilator was included to reduce the blood pressure to <140/90. 1. What is the diagnosis for this individual? (3 pts) 2. Name the sites of action, and describe the purpose, for the three pharmacologic agents prescribed for this individual: (9 pts) o Oral diuretic o Beta-blocker o Vasodilator 3. What was the cause of the retinal hemorrhages? (3 pts) 4. Outline the usual steps in the medical treatment of hypertension. (4 pts) 5. Write the equations for determining: (6 pts) o mean arterial blood pressure (MABP) o blood pressure (BP) o pulse pressure (PP) A 5'8", 240 lb., 52-year-old project manager went in for a physical exam. His blood pressure was > 180/115 on three separate days. Further examination showed normal to low plasma renin activity, elevated total peripheral resistance (TPR), cardiac output (CO) of 7.2 L/min, X-ray evidence of left ventricular hypertrophy, retinal hemorrhages, and mild polyuria. Recommended therapy included weight reduction to his ideal level, a low-salt diet (<2 gm/day sodium), prudent exercise, and a reduction in alcohol consumption (<3 oz whiskey/day). This change in lifestyle did little to change the condition. Medication was initiated in the form of an oral diuretic and progressed to a beta-blocker. Eventually a vasodilator was included to reduce the blood pressure to <140/90. 1. What is the diagnosis for this individual? (3 pts) 2. Name the sites of action, and describe the purpose, for the three pharmacologic agents prescribed for this individual: (9 pts) o Oral diuretic o Beta-blocker o Vasodilator 3. What was the cause of the retinal hemorrhages? (3 pts) 4. Outline the usual steps in the medical treatment of hypertension. (4 pts) 5. Write the equations for determining: (6 pts) o mean arterial blood pressure (MABP) o blood pressure (BP) o pulse pressure (PP)
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Answer 1 The individual is diagnosed with malignant hypertension Answer 2 Oral diuretics are widely ... View the full answer
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