Consider the hypothetical serine protease below, which shows the specificity pockets. The S pocket has a...
Fantastic news! We've Found the answer you've been seeking!
Question:
Transcribed Image Text:
Consider the hypothetical serine protease below, which shows the specificity pockets. The S₁ pocket has a glutamic acid in the bottom, the S₂ pocket is small and hydrophobic, and the S; pocket is deep and hydrophobic. Suggest an amino acid sequence that this protease would cleave. R3 Arg-lle-Val lle-Arg-Val Arg-Val-lle Val-Arg-lle Val-Ile-Arg lle-Val-Arg S₂ S1 & Which of the following sequences would this protease cleave? I R₁ S₁' The S₂ pocket is small and hydrophobic. Consider the size of the amino acid side chain that could fit in this pocket. Is the side chain more likely to be hydrophobic (nonpolar) or polar? The S₁ pocket has a negative charge. Consider the charge of the amino acid likely to interact with this pocket. The S₁ pocket is deep and hydrophobic. Look for a bulky hydrophobic side chain for the corresponding amino acid. Consider the hypothetical serine protease below, which shows the specificity pockets. The S₁ pocket has a glutamic acid in the bottom, the S₂ pocket is small and hydrophobic, and the S; pocket is deep and hydrophobic. Suggest an amino acid sequence that this protease would cleave. R3 Arg-lle-Val lle-Arg-Val Arg-Val-lle Val-Arg-lle Val-Ile-Arg lle-Val-Arg S₂ S1 & Which of the following sequences would this protease cleave? I R₁ S₁' The S₂ pocket is small and hydrophobic. Consider the size of the amino acid side chain that could fit in this pocket. Is the side chain more likely to be hydrophobic (nonpolar) or polar? The S₁ pocket has a negative charge. Consider the charge of the amino acid likely to interact with this pocket. The S₁ pocket is deep and hydrophobic. Look for a bulky hydrophobic side chain for the corresponding amino acid.
Expert Answer:
Related Book For
Posted Date:
Students also viewed these accounting questions
-
Is a random mutation more likely to be beneficial or harmful? Explain your answer.
-
Which type of asset is more likely to be liquidated for close to its full market value in the event of financial distress: a. An office building or a brand name? b. Product inventory or raw...
-
a Research Problem Are crimes more likely to be committed on certain days of the week Statistical Hypotheses H0 PMon PTue PWed PThu PFri PSat PSun H1 H0 is false Decision Rule Reject H0 at 01 level...
-
A horizontal cross section of a concrete bridge pier is a regular hexagon (six sides, all equal in length, and all internal angles are equal), each side of which is 2.50 m long. If the height of the...
-
Refer to the 2011 balance sheet for Arctic Cat in Appendix A. What is the par value per share of its common stock? Suggest a rationale for the amount of par value it assigned.
-
A coach is choosing 4 students to go to a badminton competition (the order of selection does not matter). There are 20 and 15 girls to choose from, and the coach chooses randomly so everyone an equal...
-
George Edmonds, the new accountant for Zigler Company, has recommended the preparation of income statements reporting contribution margin rather than statements reporting gross profit. He states that...
-
Alarico Printing owned a piece of equipment that cost $16,200 and on which it had recorded $9,000 of accumulated depreciation. The company disposed of the equipment on January 2, the first day of...
-
Read the following letter and help Shady Slim with his tax situation. Assume that gross income is $172,900 (which consists only of salary) for purposes of this problem. December 31, 2022 To the...
-
A binary mixture of mole fraction zj is flashed (o conditions T and P, Fur one of the following determine: the equilibrium mole fractions x1 and y1 of the liquid and vapor phases formed, the molar...
-
For this assignment, use your analysis of the brand's current digital media presence to develop the framework for a new digital campaign. For your new campaign, describe relevant research methods,...
-
Use the 2016 marginal tax rates to compute the income tax owed by the following person. Single male, no dependents. Gross income:$82,000 Adjustments: $2000 Deductions: $27,000 mortgage interest $4278...
-
In not less than five hundred words, summarize the definition of forensic psychology, the history of forensic psychology, conflicts between psychology and the law, and the future of the relationship...
-
2. Explain importance of Turing Test. 3. Give any two real-life applications of Al in detail. 4. Write down the PEAS description for the following problems: I. Traffic light agent. II. Robotic Agent...
-
Before responding to this discussion, complete the Checklist for Attitudes About Patients and Families as Advisors here, A CHECKLIST FOR ATTITUDES ABOUT PATIENTS AND FAMILIES AS ADVISORS Use this...
-
Lukow Products is investigating the purchase of automated equipment that will save $130,000 each year in direct labor and inventory carrying costs. This equipment costs $780,000 and is expected to...
-
Six frogs are trying to cross a pond by jumping between stones. Alma, Ben, and Carl are heading East; while Xavier, Yolanda, and Zanjoe are heading West. Each frog can jump just onto an adjacent...
-
Under what conditions is the following SQL statement valid?
-
Foresters want to estimate the average age of trees in a stand. Determining age is cumbersome, because one needs to count the tree rings on a core taken from the tree. In general, though, the older...
-
(Show that the variance is minimized for a fixed cost with the cost function in (3.12) when nh NhSh/ch, as in (3.13). Hint: Use Lagrange multipliers.
-
Potential jurors in some jurisdictions are chosen from a list of county residents who are registered voters or licensed drivers over age 18. In the fourth quarter of 1994, 100,300 jury summons were...
-
The Forensic Accounting Box of this chapter noted that forensic accounting techniques are being used to help pick stocks for investing. How might identifying accounting concerns be useful for...
-
In the corporate social responsibility highlight regarding Starbucks on page 528 in this chapter, it was stated that Starbucks believes in measuring and monitoring the company's CSR progress. The...
-
The fiscal year 2017 annual report of General Mills, Inc. is available on this book's Website. Required a. How many shares of common stock is General Mills authorized to issue? How many common shares...
Study smarter with the SolutionInn App