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1) Consider the two structures below and answer all the questions: B Caffeine, a central nervous system Ibuprofen, a non-steroidal (CNS) stimulant anti-inflammatory drug Figure Q1 a) Reproduce the structures and indicate the hybridisation states (e.g. sp,sp2,sp3 ) of each of the carbon atoms in both compound A and compound B. (4+6marks) b) Caffeine is known as an alkaloid. It is poorly soluble in cold water. Give the definition of an alkaloid (citing the source used) and suggest a simple chemical treatment that would help solubilise caffeine in water. (2 mark) c) Reproduce compound B of Figure Q1 and label with a the chiral carbon. (1 mark) d) Redraw the 3D structure of B, then circle and label the groups around the chiral centre according to the Cahn-Ingold-Prelog (CIP) priority rules. Assign the resulting R or S stereodescriptor to the chiral centre