Metabolic Effect Effects of Insulin on Carbohydrate and Lipid Metabolism Glucose uptake (muscle, adipose) Glucose uptake (liver) Glycogen synthesis (liver, muscle) Glycogen breakdown (liver, muscle) Glycolysis, Acetyl CoA production (liver, muscle) Fatty acid synthesis (liver) TAG synthesis (adipose tissue) Metabolic Effect Glycogen breakdown (liver) Glycogen synthesis (liver) Glycolysis (liver) CHEM441B Metabolic Integration Gluconeogenesis (liver) Fatty acid mobilization (adipose tissue) Effects of Glucagon on Carbohydrate and Lipid Metabolism Ketogenesis (liver) Glycolysis (muscle) Glycogen breakdown (muscle) Target Enzymes/Proteins GLUT4 How is it regulated? Target Enzymes/Proteins How is it regulated

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