Pyridines substituted with leaving groups at the 2- or 4-position readily undergo nucleophilic aromatic substitutions. Provide a

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Pyridines substituted with leaving groups at the 2- or 4-position readily undergo nucleophilic aromatic substitutions. Provide a mechanism for the following reaction and explain why such substitutions do not take place at the 3-position. (5 marks)

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Organic Chemistry

ISBN: 978-1118133576

11th edition

Authors: Graham Solomons, Craig Fryhle, Scott Snyder

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Posted Date: Nov 16, 2020 11:53 PM

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Pyridines substituted with leaving groups at the 2- or 4-position readily undergo nucleophilic aromatic substitutions. Provide a

Question:

CI SCH3 NaSCH3 N' N. CI SCH3 NaSCH3 N' N.

Expert Answer:

Position 3 is more el... View the full answer

Organic Chemistry

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