Recall that the free energy (AG) of chemical reactions depends on several parameters: enthalpy (AH), entropy...

  

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Recall that the free energy (AG) of chemical reactions depends on several parameters: enthalpy (AH), entropy (AS), as well as the concentrations of reactants and products. Consider another reaction of glycolysis. Reaction #5 involves an isomerization of dihydroxyacetone phosphate (DHAP) to glyceraldehyde 3-phosphate (GAP). This reaction is a reversible (DHAP <-> GAP). Refer to the textbook (section 8.2) and your lecture notes for kinetic and thermodynamic parameters. Also, take a look at Table 16.1 in the textbook. The brain requires the most glucose of any organ and continuous glycolysis for its functions. In the active brain, concentrations are maintained at [DHAP] = 8.0 x 10-4 M and [GAP] =3.0 x 10-5 M. Calculate the following thermodynamic parameters. [Write numbers and units. Show your calculations below.] A) Equilibrium constant: K B) Reaction free energy at equilibrium: AG= C) Reaction free energy at standard state (T=298K, [DHAP] = [GAP] = 1 M): AG= D) Reaction free energy in the active brain: AG=_ Recall that the free energy (AG) of chemical reactions depends on several parameters: enthalpy (AH), entropy (AS), as well as the concentrations of reactants and products. Consider another reaction of glycolysis. Reaction #5 involves an isomerization of dihydroxyacetone phosphate (DHAP) to glyceraldehyde 3-phosphate (GAP). This reaction is a reversible (DHAP <-> GAP). Refer to the textbook (section 8.2) and your lecture notes for kinetic and thermodynamic parameters. Also, take a look at Table 16.1 in the textbook. The brain requires the most glucose of any organ and continuous glycolysis for its functions. In the active brain, concentrations are maintained at [DHAP] = 8.0 x 10-4 M and [GAP] =3.0 x 10-5 M. Calculate the following thermodynamic parameters. [Write numbers and units. Show your calculations below.] A) Equilibrium constant: K B) Reaction free energy at equilibrium: AG= C) Reaction free energy at standard state (T=298K, [DHAP] = [GAP] = 1 M): AG= D) Reaction free energy in the active brain: AG=_

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A Equilibrium constant K The equilibrium constant K can be calculated using the reaction quotient Q ... View the full answer